'Obesity, Poor Metabolic Health Spread More Virus (viral load deep dive)'

'Various studies have found a correlation with obesity, poor metabolic health and higher viral loads. This show summarize the research, suggesting it\'s our moral obligation to get and stay metabolically healthy.   Support Healthy Hydration and Exercise Performance with this new Electrolyte Stix by MYOXCIENCE Nutrition: https://bit.ly/3uAWrV6 Pre-order by 10/31 for the discount   Links to articles: https://bit.ly/3B2Jfd5  -------------Sleep & Camera Tools You NEED!-----------------------  Best Sleep Mask: http://bit.ly/2AIVbDV  Blue Blocking Glasses: http://bit.ly/blueblox  A Metabolism Book Should Have:https://amzn.to/2jUiAh5  Best Mouth Tape (Nexcare): https://amzn.to/31qJayh  Red Headlamp (wear this at night around your house): https://amzn.to/2YzMGtw  Breath Right Strips: https://amzn.to/31t5VSl  -----------------------------------------Show Notes--------------------------------------  0:00 intro  05:30 Use food shortages to favorably change your habits. 07:22 Elevated glucose levels directly promote viral replication and cytokine expression  09:21 Overweight people have prolonged viral shedding, more virus in their breath and more viral variability. More viral load means more viral replication. 10:50 Body fat is a reservoir for viruses and is linked to prolonged viral shedding.  13:50 Individuals with higher body mass index have a higher viral load.  Metabolically healthy people have less viral load (less replication), a shorter shedding period and a milder course of infection.  15:30 Higher viral load may have implications in transmissibility of the virus, especially in the more transmissible variants. Higher viral load seems to create a higher antibody response. 16:50 Detectible serum  viral load is closely associated with drastically elevated interleukin 6 level in critically ill  patients. Interleukin 6 is a chemical messenger used by your immune system to respond to immunologic triggers. People with obesity and chronic inflammation have chronically higher levels of interleukin 6. When these folks encounter an illness like , there could be far more damage from the cytokine storm.  18:00 Measuring interleukin 6 is expensive. An option is to measure CRP. If CRP is elevated, it is likely that interleukin 6 and other cytokines are elevated. Smoldering inflammation is often the result of under exercising and over-consumption of packaged foods.  19:00 There is a strong correlation between common co-morbidities and levels of viral load. These co-morbidities are caused by our diet and lifestyle choices.  19:40 Exhaled aerosol increases with C*19, age and obesity. Viral load increases with increasing age and increasing BMI. 23:20 Gut dysbiosis may be the cause of the viral/bacterial co-infections found in the lungs of COVID patients.  24:58 Highly processed carbs with fat cause dysbiosis and compromise the integrity of your intestinal epithelial tissue and can alter the gut/lung axis. Microbiota can directly or indirectly impact the outcome and differential viral infection.  25:40 The virus and other pathogens can hijack their way into the body on gram negative bacterial lipopolysaccharides, especially if you are eating processed foods.  27:18 ACE2 receptor modulation by viral infection can significantly influence the content and leakage from the gut.  Severe forms of are connected with pronounced GI symptoms and opportunistic pathogens in gut microbiota.  29:29 Poor gut health may mean that you may have weakened immunity or immune response in your lungs. 29:45 Sedentary people have reduced muscle function, increased cardiovascular risk factors, impaired immune function, immunosenescence, and increased incidence of lung inflammation and bacterial pneumonia. This leads to more severe viral infections.  30:15 People who regularly exercise have improved immune responses, decreased incidence of infection, improved lung function, stronger and longer lasting antibody responses to vaccinations, mitigated immunosenescence and more ability to fight inflammation. This leads to less severity of viral infection.' 

Tags: intermittent fasting , obesity , low carb diet , low carb , Insulin , gut health , leaky gut , insulin resistance , metabolic health , dysbiosis

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