'New research highlights a critical interplay between autophagy and gut health, specifically with regard to supporting the integrity of the gut barrier. Support your Intermittent Fasting lifestyle with Berberine HCl & Lipoic Acid by MYOXCIENCE: https://bit.ly/berberine-biotin-ala-stack Use code Podcast to save Link to show notes and research: https://bit.ly/2RCnAI2 New to fasting? Give ProLon a try: https://bit.ly/3wY9GQ8 Discount Code (15% off all Products): MetabolicMike -------------Sleep & Camera Tools You NEED!----------------------- Best Sleep Mask: http://bit.ly/2AIVbDV Blue Blocking Glasses: http://bit.ly/blueblox Gravity Blanket (use code HIH10 to save): http://bit.ly/cooling-gravity-blanket A Metabolism Book Should Have:https://amzn.to/2jUiAh5 Best Mouth Tape (Nexcare): https://amzn.to/31qJayh Red Headlamp (wear this at night around your house): https://amzn.to/2YzMGtw Breath Right Strips: https://amzn.to/31t5VSl Best iPhone Stabilizer: https://amzn.to/2IuCFFw Sony Vlog Cam: https://amzn.to/2DhRV4j My Interview Camera C100 ii: https://amzn.to/2EC5NE8 Vlog lens: Canon EF-S 17-55mm f/2.8 IS: https://amzn.to/2IGlfSo Good Audio: Rode VMPRPLUS Videomic Pro: https://amzn.to/2v9W9cm -----------------------------------------Show Notes-------------------------------------- 0:00 Intro 02:05 The best way to enhance autophagy is with diet and exercise. 02:44 mTOR is the autophagy break and AMPK is the gas. AMPK also puts the break on mTOR. 03:25 These enzymes cannot be directly tested. 04:20 If your glucose is high in a fasted morning test, you may not be experiencing autophagy. 04:40 Your body upregulates APT with activity after your night’s fast. This increases AMPK and puts the breaks on mTOR. 05:40 mTOR is activated in the post meal window. This helps you body take the nutrients. 07:00 Exercise stimulates AMPK, as does intermittent fasting and taking berberine hydrochloride. 07:40 Paneth cells are key at releasing antimicrobial peptides which keep pathogens from entering. 09:40 Endotoxin/LPS (lipopolysaccharides) are found on the surface of gram-negative bacteria. Because of these, many of us with leaky gut have low grade sepsis after every meal. 10:44 Paneth cells and intestinal stem cells are intimately connected to the autophagy process. 12:20 Paneth cells control your intestinal stem cells. Stem cells help replenish and repair damaged cells. 14:00 Intestinal permeability can be tested via Dunwoody Labs. 14:22 Tight junction proteins are the mortar for your gut lining. 15:50 Dysfunction in your gut endothelium cross-talks with lung and cardiovascular endothelium. *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.'
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